Population aging is a major social problem that China is facing. Scientific prediction and correct analysis of population aging are important for resource allocation, policy formulation, and service provision. To this end, this paper proposes a population prediction framework based on grey models to predict and analyze regional differences in China's aging status. Firstly, we construct three indicators, i.e., total population, aged population, and proportion of the aged population, to reflect the aging status of a region. Secondly, we develop a grey model framework to predict and analyze aging differences in the eastern, central, and western regions of China. Finally, according to the prediction and analysis results of the three aging indicators, we suggest some corresponding countermeasures to address the challenges of China's future aging problem.