The purpose of the paper is to explore the influencing factors of the patient’s attitude to the medical service price. Literature analysis and expert interviews are used to design the questionnaire. Using a convenient sampling method to extract 600 patients from the five areas of Beijing, Tianjin, Hebei, Shandong and Liaoning. Combing grey relational analysis with Cochran-Mantel-Haenszel (CMH) statistical analysis to explore the influencing factors of the attitude in the medical service price. The results show that region, gender, age, education, professional title, income by month, medical insurance, commercial medical insurance and work unit are related to the distribution of patients’ attitude of medical service price by CMH statistical analysis. The sorting of Grey relational grade is Region (0.997)> Gender (0.939)> Commercial Medical Insurance (0.828)> Level of Medical institution (0.736)> Income by month(RMB) (0.701)> Medical insurance (0.644)> Professional Title (0.598)> Work unit (0.545)> Age (0.481)> Education (0.462); The grey relational grade of those respondents surveyed who are living in Shandong province (0.821), female (0.797), don’t buy commercial medical insurance (0.846), go to the tertiary hospital lately (0.831) and have income of 4000-6000 yuan by month (0.840) are higher than others. The current medical service price is higher than the reasonable level, especially in the operation fee and examination fee involving large consumables. The patient’s satisfaction with the price of medical service items is different in different variables, and the main influencing factors are as follows: Region, Gender, Commercial Medical Insurance, Level of Medical institution and Income by month (RMB).